Cosmate®HPR10, pia inaitwa Hydroxypinacolone Retinoate 10%,HPR10, yenye jina la INCI Hydroxypinacolone Retinoate na Dimethyl Isosorbide, imeundwa na Hydroxypinacolone Retinoate pamoja na Dimethyl Isosorbide, ni ester ya all-trans Retinoic Acid are natural derivative and synwhitic acid, ya vitamini A, yenye uwezo wa kumfunga kwa vipokezi vya retinoid. Kufunga kwa vipokezi vya retinoid kunaweza kuboresha usemi wa jeni, ambao huwasha na kuzima kazi muhimu za seli.